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10.1038/s41423-020-0366-2 89 LiangY.ShenS.YeX.ZhangW.LinX

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The GLP-1 ceiling problem Even with the most effective GLP-1 therapies currently available, a significant proportion of patients do not achieve clinically optimal weight loss outcomes

Purification and Detection High performance liquid chromatography (HPLC) purification: The synthesized polypeptides need to be purified by HPLC to remove impurities and unreacted raw materials, ensuring that the purity meets the pharmaceutic-grade standard

BPC-157 has shown particular promise in gastrointestinal applications, while TB-500 has demonstrated potential cardiovascular benefits