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RGN-259 promoted rapid healing of corneal epithelial defects, improved Mackie classification disease stage, and produced significant improvements in ocular discomfort, foreign body sensation, and dryness, with no significant adverse effects

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For each patient, the risk-benefit tradeoff critically depends on a patients clinical characteristics and their preferences and clinicians recommendations, senior study author Rong Xu, PhD, professor and director of the Center for AI in Drug Discovery at Case Western Reserve University, told Healthline

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Finally, the metastable sets were computed using the PCCA+ spectral clustering implemented in pyEMMA