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J Cell Biochem , 61:410419

doi: 10.1006/abio.1993.1529 53 MhamdiA.HagerJ.ChaouchS.QuevalG.HanY.TaconnatL.et al

doi: 10.1016/S0020-7519(03)00158-9 38 de BarrosLDKoutsodontis Cerqueira-CzarC

Nature, 268(5616), 152-153

Without intrinsic factor, oral B12 cannot be absorbed at all injections are the primary treatment

Multiple residues in DET1 form hydrogen bonds and electrostatic interactions with Ube2e2, including DET1 D289 : Ube2e2 R126 , DET1 H297 : Ube2e2 T201 , DET1 D324 : Ube2e2 R88 and Ube2e2 R124 , DET1 R317 : Ube2e2 T68 (Fig