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GIP is another gut hormone that, like GLP-1, plays a role in blood sugar regulation and energy balance

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Tirzepatide is a dual-agonist that activates both GLP-1 and GIP receptors

Long-acting dosage forms have more advantages in blood sugar control due to their longer half-life and stable blood concentration

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Activity of complex I was quantified based on the protocol described by Spinazzi et al