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These areas tend to respond better to the treatment compared to larger zones with more fat accumulation

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PT150 is a novel glucocorticoid receptor antagonist, with reduced affinity for progesterone receptors relative to mifepristone, that has been shown to attenuate glucocorticoid-dependent behavioral and physiological outcomes in preclinical models (12-14)

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However, the FDA requires a boxed warning for thyroid C-cell tumors based on rodent studies, though human relevance remains uncertain

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