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Multi-Target Sleep + Stress + LH Beyond sleep: modulation of cortisol/ACTH, stimulation of LH, analgesic effects and applications in addiction (opiates, alcohol)

Neelakantan, H

The debilitating, slow damage created by high levels of blood sugar (glucose) destroys everything from your blood vessels to your eyes, kidneys, and nerves over time due to oxidative stress (remember the free radicals or reactive oxygen species (ROS)?)

For context, most GLP-1 medications require consistent use for weeks or months to start working at full therapeutic capacity

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Cell 3 , 12 (2011)