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10.1016/S0021-9258(17)37366-0 3 AstrupA

Melanotan1/MSHlike agonism increases cAMP and PKA signaling, which inhibits NFB activation (via preservation of IB), activates CREB, induces antiinflammatory mediators (e.g., IL10), and suppresses proinflammatory cytokines (TNF, IL1, IL6, IL8, IL12), adhesion molecules, and iNOS

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Oral vaccination using microdevices to deliver -GalCer adjuvanted vaccine afford a mucosal immune response