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Because the S 8 rings in solid sulfur are held to other rings by London dispersion forces, elemental sulfur is insoluble in water

Nonetheless, the existence of a biological interplay among OS, aging, and ALS has been presumed for more than two decades [325] and it is now becoming more evident [326]

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The reason is that intravenous administration carries a risk of immunogenicity the immune system recognizes Serratiaderived molecular signatures on the enzyme as foreign, which can trigger immune reactions

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