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Expression of the CART gene is essentially confined to hypothalamic neuroendocrine neurons and limbic system circuits involved in reward processes

This does not eliminate the early inflammation needed to start repair

Connecting the N and C-terminal domains is an intermediate functional domain

Managing Side Effects Over Time Some patients experience side effects such as nausea, diarrhea, or gastrointestinal discomfort, which may influence how long they can tolerate the medication

A diet lower in refined carbohydrates reduces glucose spikes

Gradual Increase: Increase the dose every 4 weeks through incremental steps (0.5 mg, 1 mg, 1.7 mg) up to 2.4 mg once weekly