semaglutide and spironolactone Weight won't budge on : r/Semaglutide Spironolactone + Semaglutide: Safety, Interactions

Mahase E (2022)

Rybelsus (generic name: oral semaglutide) is the worlds first oral GLP-1 receptor agonist

Hsu et al used the TriNetX platform to study the association between semaglutide use and the incidence of NAION and found that it was associated with an increased risk in patients with diabetes at the 2-, 3-, and 4-year timepoints but not within 1 year of GLP-1 RA initiation

The details ( Evidence, limitations, Mechanisms and massage for patients) in first 4 comments What this means for users/patients +If someone is being treated with semaglutide and has risk factors for optic nerve issues (for example: previous NAION in one eye, glaucoma, optic disc crowding, severe diabetic retinopathy, major vascular disease), then this potential risk should be discussed with their ophthalmologist and prescribing physician

Try gentle swirling, and if it persists, switch to acetic acid water

These shifts can affect other hormones in your body as well, including those related to stress and energy balance