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CXCL5, a secreted chemokine that recruits neutrophils, has been linked to a reduced TEER and ZO-1 expression mediated via activation of p38 MAPkinase pathways in primary BECs (Yu et al., 2021)
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If we can utilize safe quantities of methionine to control these factors, we cancel out any potential effect methionine itself would have on mTOR
Additionally, recent studies have identified bacterial DNA in human and mouse adipose tissues 20,21
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