However, prior to secretion the amino terminal is cleaved resulting in GLP-1 (7-36 amide) which is the major form in human plasma and is commonly referred to as GLP-1 (89)
Some individuals may experience swelling at the injection site, mild diarrhea, or itching
Furlow WL
Nevertheless, individual patient factorsincluding age, menopausal status, baseline bone health, and degree of weight losswarrant consideration in clinical practice
Williams R, Karuranga S, Malanda B, et al
Excretion Pathways Radiolabeled studies in humans established PT-141s elimination pathways: 64.8% of administered dose recovered in urine 22.8% of dose recovered in feces Complete elimination occurring within several days No evidence of accumulation with repeated administration The predominantly renal excretion pattern and absence of accumulation support the approved dosing regimen of no more than one dose per 24 hours and maximum eight doses per month