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These limitations dont invalidate the positive safety findings but do suggest that comprehensive medical supervision remains appropriate for anyone using AOD-9604, particularly for off-label applications or extended treatment periods

Some prescribers and users prefer microdosing schedules (splitting the weekly dose into smaller, more frequent injections), which aren't shown on this standard chart

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The concentrations of glucose and acetic acid were monitored by HPLC (LC-10AT, Shimadzu, Japan) using an Amines HPX-87H column (Bio-Rad, USA) and a refractive index detector (RID-10A, Shimadzu, Japan)