Its core physiological function is to catalyze the methylation of nicotinamide (NAM, a key precursor for NAD+ synthesis) with Sadenosylmethionine (SAM) to produce 1methylnicotinamide (1MNA)
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The process may have been delayed or the application withdrawn
Guo L, Moss SE, Alexander RA, Ali RR, Fitzke FW, Cordeiro MF
The scanning range was 185300 nm at a speed of 20 nm/min, the bandwidth was 1 nm, and the spectra were accumulated 5 times
Corsini, EM, Mitchell, KG, Correa, AM, Morris, VK, Antonoff, MB, Zhou, N, Hofstetter, WL, Mehran, RJ, Rice, DC, Roth, JA, Sepesi, B, Swisher, SG , Vaporciyan, AA, Walsh, GL