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It represents a fundamental evolution in how metabolic medicine approaches obesity

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These include GLP-1 medications like semaglutide and tirzepatide, when clinically appropriate

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Although this study provides valuable insights into the effects of GLP-1 analogs on MC4R deficiency pathology, there are several limitations that must be addressed in future studies

The Glucagon-like peptide-1 receptor agonist, exendin-4, ameliorated gastrointestinal dysfunction in the Wistar Kyoto rat model of Irritable Bowel Syndrome