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GABAergic disinhibition and impaired KCC2 cotransporter activity underlie tumor-associated epilepsy

Traditionally consumed in various cultures for their health-promoting effects, Ajwa dates have recently been explored for their neuroprotective potential, particularly regarding oxidative stress and neuroinflammationtwo key pathological mechanisms implicated in the development of depression and other neuropsychiatric disorders

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There are several mechanisms: receptor-mediated transport, EVs express a variety of receptors and ligands on the surface, which can bind to the receptors on the surface of BBB endothelial cells, triggering endocytosis, thus realizing transmembrane transport (133)

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