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GLP-1 receptor agonists as pharmacologic treatment for obesity after spinal cord injury: clinical considerations
Mean weight reductions were greater with all cagrilintide doses (roughly 6.0% to 10.8%) than with placebo (3.0%), and the top 4.5 mg dose modestly out-performed the active comparator, once-daily liraglutide 3.0 mg (10.8% vs 9.0%)
JCI Insight (2020) 4
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GLP-1R biased signalling also occurs in WT receptors following activation with modified peptide agonists (59)
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