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As per the UK SmPC, the dose is escalated every 4 weeks to reach the target dose of 2.4 mg, with the option to delay a step by 4 weeks if not tolerated
I never went above 0.5 mg
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Keeping Track of Symptoms Writing down when the pain started, what it feels like, and what makes it better or worse can help during doctor visits
The CD38 glycohydrolase and the NAD sink: implications for pathological conditions
It begs for confirmation and a bigger trial, and it raises the question of whether this is a pleotropic effect of the drug, versus only a weight loss effect. TAVR-MET trial Thirugnanam and colleagues randomized 260 patients (mean age 73 years
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