6.2 Linking GSH/GSSG to Transcriptomic and Proteomic Regulation Transcriptomic and proteomic data can connect metabolite changes to functional modules: GCLC/GCLM/GSS for synthesis, SLC7A11 for substrate acquisition, GSR/GPX/GST for regeneration and use, pentose phosphate pathway enzymes for NADPH supply, and NRF2-KEAP1 signaling for coordinated antioxidant adaptation
MDA, malondialdehyde
instead, they form a dynamic and adaptive response network in which impairment of one branch often triggers compensatory activation of another
Dermicu (30 mL)
Methionine is an essential amino acid and antioxidant that synthesizes proteins, and cysteine is a nonessential amino acid that can help reduce inflammation and increase communication between immune cells
Am J Respir Cell Mol Biol 38 : 509516 Reddy NM, Kleeberger SR, Kensler TW, Yamamoto M, Hassoun PM, Reddy SP 2009 Disruption of nrf2 impairs the resolution of hyperoxia-induced acute lung injury and inflammation in mice