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Medical monitoring with baseline and follow-up trichoscopy tracks whether your hair is recovering (good its pure TE) or whether follicle miniaturisation is progressing (not good its FPHL and needs treatment)

Initial doses typically range from 100 to 400 milligrams per day, divided into multiple doses

Emerging personalized medicine strategies such as genetic testing and biomarker profiling may eventually help predict treatment response and guide dosing adjustments

Side effects: mild nausea possible

Research documents lipolytic mechanisms through interaction with the beta-3 adrenergic receptor pathway in adipose tissue

Nevertheless, use of metformin may decrease vitamin B 12 status: a meta-analysis of four short-term intervention trials (up to 4 months duration) in patients with type 2 diabetes found that metformin use decreased serum cobalamin concentrations by 57 pmol/L, which could have clinical implications if such patients have suboptimal vitamin B 12 status (146)