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: Phase III REGENCY trial demonstrated 46.4% complete renal response vs 33.1% with standard therapy alone Significant improvement in multiple secondary endpoints including proteinuria reduction Consistent safety profile with known oncology indications First anti-CD20 monoclonal antibody with phase III evidence in lupus nephritis : - More convenient administration schedule: four initial doses in first year, then twice-yearly infusions - Option for 90-minute infusions after initial dose - Maintains standard therapy alongside biologic treatment - Requires monitoring for infections and infusion-related reactions "This approval provides a much-needed new option for these patients," said Levi Garraway, MD, PhD, chief medical officer at Roche, highlighting the significant unmet need in lupus nephritis management

Two clients both at the same starting weight

The analysis is particularly important because it focused on the drugs' long-term effects rather than short-term outcomes

The convenience of a weekly injection adds to the appeal of the medication

None of these are approved uses yet

This thoughtful addition enhances the overall experience, making the treatment comfortable and well-tolerated