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PMC 3134129
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When combined, the risk of serotonin syndrome, a potentially life-threatening condition, increases, as both medications can influence serotonin levels in the brain. Serotonin might be the bodys feel good chemical, but serotonin syndrome may cause nausea, vomiting, diarrhea, and tremors when its mild or high blood pressure, racing heart rate, seizures, and fainting when its more severe
L-buthionine sulfoximine (BSO) is a specific and selective inhibitor of -glutamylcysteine synthase and consequently of GSH synthesis [2]
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