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Side effects are uncommon but may include mild digestive discomfort at higher doses
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Although statistically significant, these effects remain smaller than those achieved with retinoids or growth factor formulations
These medications are given as once-weekly subcutaneous injections, with doses gradually increased over a five-month period to reach the maximum level
Franchi et al., Arginine metabolism in tumor-associated macrophages in cutaneous malignant melanoma: evidence from human and experimental tumors
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