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Safety data : CagriSema builds on semaglutide's 7+ year track record

Bile acid-mediated activation of TGR5 (Tolhurst et al., 2012), LPS, and other metabolites such as indole (Pathak et al., 2017)

At week 12, women in the collagen group displayed significantly improved skin scores for wrinkle, elasticity, hydration, radiance, and firmness compared with placebo control values (via VISIA skin analysis system, Cutometer , and Skin Quality Visual Analogue Scale)