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Clinical trials supporting their approval typically lasted 68 to 72 weeks, but extension studies have followed patients for longer periods
ifosfamide, cisplatin and doxorubicin), are associated with decreased carnitine levels and occasionally with true carnitine deficiency [36, 37]
Consider staying at your current dose for an additional 2-4 weeks if you experience: Persistent nausea or vomiting lasting more than 3 days Rapid weight loss exceeding 3-4 lbs per week Severe constipation or diarrhea Signs of dehydration Significant injection site reactions The goal is to reach the maintenance dose gradually
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