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GLP-1 receptor agonists work by mimicking this endogenous hormone , binding to GLP-1 receptors found throughout the body

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Alternatively, some people do better on a lower maintenance dose long term rather than pushing to the maximum dose

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Mortality and major complications (MI, stroke, renal failure) were marginally lower in the steroid group (OR 0.83), while other morbidities were significantly reduced: infections (OR 0.64), delirium (OR 0.79), respiratory failure (OR 0.69)

Mller F, Fromm MF (2011) Transporter-mediated drug-drug interactions