If you are on 0.25 mg of semaglutide during your titration phase, a 5mg vial might last 20 doses, or roughly five months at weekly dosing
As underlying mechanisms, it has been reported that GLP-1 causes renal vasodilatation, increases renal blood flow, increases glomerular filtration rate, inhibits the Na + /H + exchanger 3 in proximal tubule and decreases sodium, bicarbonate and water reabsorption [12, 14]
Suggested Use: Intended for use in healthy adults and as part of a healthy, balanced diet and exercise program
In fact, 83.5% of the patients who developed complications at the end of the study already had DR at baseline, and the level was not described in the paper
A 10mg vial at a maintenance dose of 8mg weekly lasts roughly 1.25 weeks, so you would need approximately 4 vials per month at full dosing
Additional drugs from other companies that have signed an MFN will be made available through the website in the coming months