Vitamin B12 overdose Symptoms: Headache Nausea and vomiting Bloating Diarrhea Fatigue and weakness Tingling in hands and feet Dizziness Itchy, burning skin Acne High blood pressure There are few studies for vitamin B12 overdose, but some medical experts suggest potential harm from B12 overload: May increase the risk for heart attack and stroke Too much vitamin B12 and folate during pregnancy may increase the risk of autism in offspring Could increase the risk for cancer May shorten lifespan High C-reactive protein (CRP) combined with vitamin B12 overload decreases the survival of cancer patients Its unlikely that high vitamin B12 can occur without the overuse of high-efficiency oral or injectable B12
Folate is converted into its active form (5-methyltetrahydrofolate) through the folate cycle, and MTHFR is directly responsible for the creation of folates active form
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Methionine plays an important role in breaking down fats and may help reduce the accumulation of excess fat in the liver
If you are self-supplementing with high-dose B12 without medical indication, discuss this with your GP