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Gaps in safety assessment encompass limited long-term data in vulnerable populations, an incomplete understanding of horizontal gene transfer related to antimicrobial resistance, and uncertainty regarding the systemic impact of prolonged microbiome modulation, particularly with next-generation strains lacking a long history of safe use (142)

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Nanoscale Research Letters 2013

Furthermore, vitamin E supplementation decreased damage of DNA in breast cancer patients receiving chemotherapy (45)

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