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Retrieved 20 April 2012

Why havent GLP-1 agonists been approved for NASH

At these concentrations, the GLP-1 receptor activation is sufficient to engage anti-inflammatory pathways without triggering the gastrointestinal side effects that make full-dose therapy difficult for many patients

Patients may need prolonged monitoring and supportive care

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To prevent skin irritation and ensure proper absorption, you should rotate the injection site with each weekly dose