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Of interest, in the randomized trial by Jensterle et al
Sposito, C
Biochemical tests demonstrated increased levels of D-2-hydroxyglutaric acid and citric acid cycle intermediates (such as succinic acid and lactic acid) in blood, urine, and cerebrospinal fluid, and increased protein concentration in cerebrospinal fluid [58] and -aminobutyric acid [59]
The cardiorenal protective effects of finerenone, a novel nonsteroidal mineralocorticoid receptor antagonist (MRA), in patients with diabetes and CKD have also been revealed in recent years [11]
The New England Journal of Medicine Testosterone Trials further demonstrated improvements in sexual function, physical function, and vitality in men over 65 with low testosterone (Snyder et al., 2016)
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