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22,23,49 We provided the first evidence that secreted Klotho causes cardiac aging independent of phosphate metabolism

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Conversely, the GSSG concentration in the sample can be under estimated if the glutathione redox cycle is active or by mixed disulfide reactions with sulfhydryls other than GSH

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As previously shown, acute (5-minute) exposure to exendin-4 and exendin-D3 triggered noticeable GLP-1R internalisation, while this was much reduced with the biased agonist exendin-F1