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Transparent plastic containers or clear glass expose the peptide to ambient light and should be avoided

So on efficacy alone, orforglipron looks better, says Osama Hamdy, MD, PhD, an associate professor at Harvard Medical School and medical director of the Obesity Clinical Program at the Joslin Diabetes Center in Boston

Considerations: Proper spray technique (appropriate angle, avoiding the septum) Alternating nostrils per dose Using a saline rinse periodically to support nasal mucosal health Discontinuation and route change if persistent irritation develops Patients with allergic rhinitis, chronic sinusitis, or significant septal deviation may be poor candidates for nasal delivery and should be considered for injection or oral spray instead

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How to maximise weight loss on GLP-1 medications Here are key strategies to get the most from your GLP-1 therapy while protecting your long term health

Studies show that up to 40% of weight lost on semaglutide can come from lean muscle unless you prioritize protein and resistance training