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The presence of peripheral sensory-motor symptoms or subacute combined degeneration of the spinal cord strongly suggests the presence of a B 12 deficiency instead of folate deficiency

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Consistent absorption and systemic availability remain uncertain, and human pharmacokinetic data are lacking

Studies have shown increased fat oxidation and energy expenditure following administration

Hypokalemia: In extremely rare cases, B12 injections may lead to low potassium levels in the blood, known as hypokalemia