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Dichloroacetate Dichloroacetate (DCA), a product of water chlorination, is considered for the treatment of several disorders including genetic mitochondrial diseases and some hyperproliferative conditions 82
3A, Table S2)
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CAR-T cells are genetically engineered to express a chimeric receptor composed of an antibody against a tumor antigen (such as CD19), a cytoplasmic domain of the zeta chain of the T-cell receptor, and a costimulator domain 42,43
Biochemical analysis showed an increase in total antioxidant capacity (TAC) and a decrease in malondialdehyde (MDA) and high-sensitivity C-reactive protein (hs-CRP) levels when compared with baseline measurements
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