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They include: Nausea the most commonly reported symptom, typically peaking in the first one to two weeks after a dose change Diarrhoea and constipation both can occur, sometimes alternating Vomiting less common than nausea but reported by some patients at higher doses Abdominal discomfort or bloating Diet-related side effects occur when patients eat too little, too quickly, or consume high-fat meals

What are the contraindications