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In the past, the FDA has sought court orders to force some compounding pharmacies to stop production after repeated failures in sterile drug manufacturing

doi: 10.1038/s41586-022-05266-z 21 McIntyreR

In the Phase 2 clinical trial, participants generally met the following criteria: Body mass index (BMI) of 27 kg/m or above with at least one weight-related comorbidity (such as hypertension, dyslipidaemia, or obstructive sleep apnoea), or a BMI of 30 kg/m or above without comorbidities

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Sixteen studies were included in the quantitative synthesis, comprising a total of 6,098 participants