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6.2 Potential pathophysiological mechanisms of gut microbiota and metabolite SCFAs in cytokine abnormalities SCFAs (such as acetate, propionate, and butyrate) activate receptors like FFAR2/3 and Gpr109a and inhibit histone deacetylase (HDAC), collectively suppressing the activation of the NF-B signaling pathway, thereby downregulating the expression of pro-inflammatory cytokines (202204)

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doi:10.3390/nu15092209 Patrick L

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Isotopically labeled analog maintains identical chromatographic and ionization behavior to the native compound

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