Your dosage, ramping schedule, and so many other details should be decided between you and your provider to maximize results and avoid side effects as much as possible
However, in 2007 the FDA put these trials on hold because some participants experienced increased blood pressure after dosing
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( ad ) Mean (SE) change from baseline in fasting free fatty acids, n = 68 for AMG 133 and n = 6 for placebo at Day 1 (A), fasting triglycerides, n = 6 for AMG 133 and n = 6 for placebo at Day 1 (B), fasting total cholesterol, n = 68 for AMG 133 and n = 6 for placebo at Day 1 (C), fasting LDL, n = 6 for AMG 133 and n = 6 for placebo at Day 1 (D) after multiple ascending doses of AMG 133 or placebo
Diabetes Care 37, 21592167
J Clin Endocrinol Metab 66: 422429, 1988