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This LASSS-HGF strategy could be adaptable to aging 32,41,42,68,69,70 and several disorders and diseases that show the generation and accumulation of nitrated HGF and particular nitrated proteins at specific sites, including cardiovascular damage 71,72 , chronic obstructive pulmonary disease (COPD) 73 , colon and lung cancer 74,75,76 , Alzheimers and Parkinsons diseases 44 46 ,77,78
Aquaporin-4 and epilepsy
At present, numerous interventional strategies have demonstrated nephroprotective effects by targeting tubular cell death in DKD (173, 176, 200, 204206)
However, CuCl 2 and Cu(OAc) 2 significantly upregulated the extracellular protein expression of the three genes at concentrations (58 M and 580 M) without inhibiting the cell viability after 24 h
Hemoglobin A1C as a predictor of incident diabetes
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