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It may also be used as a maintenance dose after significant weight loss has already been achieved, she added
One study looked at GI disturbances in adults who took 2.4 mg of semaglutide once weekly for weight management
& Nuss, J
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Elevated blood pressure and increased heart rate can also occur, especially in the first three months
Here's the mechanism: the enzyme ALDH2 (aldehyde dehydrogenase 2) oxidises acetaldehyde into acetic acid, but this process requires adequate glutathione reserves to neutralise reactive oxygen species (ROS) generated during the reaction
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