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Severe vitamin B 12 deficiency in a mouse model showed dramatic alterations in the level of DNA methylation in the brain, which might lead to neurologic impairments (103)
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But a huge number of meat eaters are also deficient and likely dont know it B12 is absorbed through the stomach, and our ability to assimilate it through the stomach wall decreases with age, as well as due to any stomach issues like IBS, Crohns, and Celiac Disease, and medications that impact the stomach like metformin, antacids, PPIs, and ibuprofen
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