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While medication is a vital tool for many, the foundation of metabolic health will always be Lifestyle Medicine
Glucagon-like peptide-1 ( GLP-1 ) receptor agonists, such as semaglutide (Wegovy) or tirzepatide (Zepbound), reduce hunger and cravings, making it easier to maintain a calorie deficit during plateaus
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10.1094/MPMI-02-17-0036-R 102 MaketonC.FortunaA
The 2026 Frontiers review lists, across this compound class: prolactin and cortisol elevations, appetite change, dysglycaemia, fluid retention, myalgia and arthralgia, injection-site reactions [1]
Bourgonje et al., 2021
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