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however, many people still dont fully understand precisely why inflammation lies at the root of most health concerns plaguing Americans today

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Conversely, macrophages similar to M2 enhance tumor blood vessel formation, immune suppression, cancer cell infiltration, and spread by emitting anti-inflammatory agents such as TGF-, PGE2, and VEGF [61]

This integrative approach not only advances our understanding of the pathophysiological mechanisms underlying depression but also supports the development of targeted clinical interventions