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Cost-effectiveness analyses must consider both direct medication costs and potential savings from improved outcomes, including reduced diabetes complications, decreased healthcare utilization, and potential cardiovascular benefits

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Many pharmaceutical companies have failed to properly warn users of the risks and side effects associated with on and off-label use

Sermorelin was historically used in diagnostic testing for growth hormone deficiency in children, though it is not currently licensed by the MHRA for therapeutic use in the UK

In the SURMOUNT-1 trial, the 5mg group averaged 16% total body weight loss over 72 weeks