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Valentino MA, Lin JE, Waldman SA Central and Peripheral Molecular Targets for Anti-Obesity Pharmacotherapy Clinical Pharmacology & Therapeutics (2010) 3

Early screenings are vital for early detection and effective treatment

Less commonly, berberine may cause headache or a bitter taste

Its thinking long term, not just focused on scale weight, but instead on how someone feels and functions in their day-to-day life

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This discovery led to focused trials for non-diabetic populations, and the results reshaped the medical communitys approach to these medications