This is going to be a trillion-dollar drug. @hubermanlab says retatrutide is the peptide thats about to change everything. Currently in a Phase III clinical trial in humans, retatrutide caused up to one-third body weight loss in just six months, with some degree of muscle sparing
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Appropriate weighted statistical tests were used for comparison of outcomes post IPTW, including weighted chi-square tests for categorical variables, and weighted t tests (mean) for continuous variables
Semaglutide is a GLP-1 receptor agonist that activates appetite-suppressing pathways in the brain, helping reduce hunger and support sustainable weight loss
Both drugs caused weight loss (with Retatrutide double the weight loss), and regained weight after withdrawal of the GLP-1R agonist