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This inflammation due to long-term aspartame consumption may decrease reduced and oxidized glutathione levels in the liver
The cysteine residues of PDI family members such as PDI, ERp57, and ERp72 contain redox-sensitive side chains and may become oxidized during redox dysregulation (Valle and Carr, 2017)
Cell & Bioscience
Glutamate can also be deaminated via glutamate dehydrogenase to regenerate -ketoglutarate and release ammonia, a mechanism well-document in vertebrates for nitrogen and anaplerotic balance 74
Human glucose-6-phosphate dehydrogenase: primary structure and cDNA cloning
While these findings are intriguing, the leap from controlled laboratory settings to the complex biological environment of the human body is significant and uncertain
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