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They act on GLP-1 receptors in the pancreas (insulin secretion, glucagon suppression), hypothalamus (appetite suppression via POMC/NPY pathways), gastric smooth muscle (delayed emptying), and peripheral tissues including adipose and immune cells

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Do not change the dose or use it more often than prescribed

Common Peptide/GLP-1 Complications and Side Effects Even though many patients tolerate these therapies well, complications are not uncommon

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