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Rowley B, Monestier M (2005) Mechanisms of heavy metal-induced autoimmunity
The safety outcomes of this meta-analysis highlighted significant gastrointestinal and neurological side effects associated with GLP-1RA interventions 31,32
ESC Guidelines on Diabetes, Pre-Diabetes, and Cardiovascular Diseases Developed in Collaboration With the EASD
In the head-to-head trial, tirzepatide actually had slightly fewer discontinuations, so the old assumption that the stronger drug is automatically harder to handle doesn't hold up
And thats what makes GLP-1 screening so crucial
A 2021 study published in Diabetes Care (the ELAD trial) found that liraglutide was associated with slower decline in cerebral glucose metabolism in patients with Alzheimer's disease, as measured by FDG-PET imaging, though clinical outcome measures showed mixed results
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